Gretchen E. Lyons
Biology
Senior Instructor
Office:
Room BBH 352G
Phone:
(773) 442-5720
Email:
g-lyons@neiu.edu
Office Hours:
Please email g-lyons@neiu.edu to arrange to meet or speak with Dr. Lyons.
CV:
Lyons, G_CV.pdf
Country:
United States
Expertise
Tumor Immunology
Introduction to Biology (BIO 100)
The Changing Natural Environment (BIO 104)
Essential Skills for Biologists (BIO 150)
General Biology I (BIO 201)
General Genetics (BIO 303)
Research Interests
Tumor Immunology
Education
Ph.D. in Molecular Biology from Loyola University Chicago (Stritch School of Medicine) and University of Chicago
B.S. in Biology from Boston College
Selected Publications
Spear, T. T., Riley, T. P., Lyons, G. E., Callender, G. G., Roszkowski, J. J., Wang, Y., Simms, P. E., Scurti, G. M., Foley, K. C., Murray, D. C., Hellman, L. M., McMahan, R. H., Iwashima, M., Garrett-Mayer, E., Rosen, H. R., Baker, B. M., Nishimura, and M. I. 2016. Hepatitis C virus-cross-reactive TCR gene-modified T cells: a model for immunotherapy against diseases with genomic instability. J Leukoc Biol., 100(3): 545-57.
Mehrotra, S., Al-Khami, A. A., Klarquist, J., Husain, S., Naga, O., Eby, J. M., Murali, A. K., Lyons, G. E., Li, M., Spivey, N. D., Norell, H., Martins da Palma, T., Onicescu, G., Diaz-Montero, C. M., Garrett-Mayer, E., Cole, D. J., Le Poole, I. C., and Nishimura, M. I. 2012. A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice. The Journal of Immunology, 189(4): 1627-1638.
Zloza, A., Lyons, G. E., Schenkel, J. M., Moore, T. V., Lacek, A. T., O’Sullivan, J. A., Varanasi, V., Williams, J. W., Jagoda, M. C., Bellavance, E. C., Marzo, A. L., Thomas, P. G., Zafirova, B., Polić, B., Al-Harthi, L., Sperling, A. I., and Guevara-Patiño, J. A. 2012. NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses. Nature Medicine, 18(3): 422-428.
Zloza, A., Lyons, G. E., Chlewicki, L. K., Kohlhapp, F. J., O'Sullivan, J. A., Lacek, A. T., Moore, T. V., Jagoda, M. C., Kumar, V., and Guevara-Patiño, J. A. 2011. Engagement of NK receptor NKG2D, but not 2B4, results in self-reactive CD8+ T cells and autoimmune vitiligo. Autoimmunity, 44(8): 599-606.
Zloza, A., Jagoda, M. C., Lyons, G. E., Graves, M. C., Kohlhapp, F. J., O'Sullivan, J. A., Lacek, A. T., Nishimura, M. I., and Guevara-Patiño, J. A. 2011. CD8 co-receptor promotes susceptibility of CD8+ T cells to transforming growth factor-β (TGF-β)-mediated suppression. Cancer Immunology, Immunotherapy, 60(2): 291-297.