Denana Miodragovic smiles into the camera while wearing a hat.
Denana
Miodragovic
Ph.D.
Instructor
Chemistry
College of Arts and Sciences
Phone
(773) 442-5773
Courses Taught
CHEM 103, CHEM 108, CHEM 110, CHEM 211, CHEM 212, CHEM 261, CHEM 262, CHEM 391, CHEM 316, CHEM 406, CHEM 413
Research Interests
Medicinal Inorganic Chemistry and Bio-Inorganic Chemistry
Education

B.S., M.S., and Ph.D. in Chemistry (2003), University of Belgrade, Serbia
Doctoral thesis:
“Syntheses and Stereochemistry of Cobalt(III) Complexes with Aromatic Amino Acids”
Adviser: Professor Slobodan Milosavljevic

Postdoctoral studies – Northwestern University, Evanston, USA 
Adviser: Professor Thomas Vincent O’Halloran
Project: Syntheses of inorganic anticancer agents based on the combination of platinum and arsenic drugs

Selected Publications

Miodragović DU, Merlino A, Swindell E, Marzo T., Bogachkov A., Ahn R., Abuhadba S, Ferraro G, Mazar AP, Messori L, and O’Halloran TV, Arsenoplatin-1 is A Dual Pharmacophore Anti-Cancer Agent, JACS, 141 (16) (2019) 6453-6457.https://pubs.acs.org/doi/abs/10.1021/jacs.8b13681

Miodragović D, Swindell E.P,Waxali Z.S., BogachkovA., and O’Hallorana T.V., Beyond Cisplatin: Combination Therapy with Arsenic Trioxide, Inorganica Chimica Acta, 496 (2019) 119030. https://www.sciencedirect.com/science/article/pii/S0020169319306048

Ðenana U.  Miodragović, Jeremy A. Quentzel, Josh W. Kurutz, Charlotte L. Stern, Richard W. Ahn, and Thomas O’Halloran, Robust Structure and Activity of Aqueous Arsenous Acid-Platinum(II) Anticancer Complexes, Angew. Chem. In. Ed, 52 (2013) 10749-10752. 
http://onlinelibrary.wiley.com/doi/10.1002/anie.201303251

Swindell, Elden; Hankins, Patrick; Chen, Haimei; Miodragović, Đenana; O'Halloran, Thomas, Anticancer Activity of Small Molecule and Nanoparticulate Arsenic(III) Complexes", Inorg. Chem. (2013), 52, 12292-12 304. http://dx.doi.org/10.1021/ic401211u

Minić Dragica M., Sumar-Ristović Maja T., Miodragović Ðenana U., Andjelković Katarina K., Poleti Dejan, Kinetics and mechanism of degradation of Co(II)-N-benzyloxycarbonylglycinato complex, J. Therm. Anal. Calorim. 7 (2012) 1167-1176. 
http://link.springer.com/article/10.1007/s10973-011-1368-1

Miodragović  Djenana U., Jovanović Dragoljub, Bogdanović Goran A., Mitić Dragana, Andjelković KatarinaSynthesis and crystal structures of 1,2,3,4-tetrahydro-9-aminoacridine tetrachlorozincate(II) monohydrate, J. Serb. Chem. Soc., 75 (2010) 1209-1218.

Sumar-Ristović  Maja T., Minić Dragica M., Poleti Dejan, Miodragović Zoran, Miodragović Ðenana, Andjelkovic Katarina K., Thermal stability and degradation of Co(II), Cd(II), and Zn(II) complexes with N-benzyloxycarbonylglycinato ligand, J. Therm. Anal. Calorim. 102 (2010) 83-90.http://link.springer.com/article/10.1007%2Fs10973-010-0748-2/fulltext.html

Mitić D, Milenković M, Milosavljević S, Gođevac D, Miodragović Z, Anđelković K and Miodragović D., Synthesis, characterization and antimicrobial activity of the Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine, Eur. J. Med. Chem. 44 (2009) 1537-1544. 
http://www.sciencedirect.com.turing.library.northwestern.edu/science/article/pii/S0020169307004082

Miodragović DU, Mitić DM, Miodragović ZM, Bogdanović GA, Vitnik ŽJ, Vitorović MD, Radulović MD,  Nastasijević BJ, Juranić IO, Andjelković KK,"Syntheses, characterization and antimicrobial activity of the first complexes of Zn(II), Cd(II) and Co(II) with N-benzyloxycarbonylglycine. X-ray crystal structure of the polymeric Cd(II) complex", Inorg. Chim. Acta 361 (2008) 86-94.http://www.sciencedirect.com.turing.library.northwestern.edu/science/article/pii/S0020169307004082

 Mitić M, Miodragović DU, Sladić DS, Vitnik ŽJ, Miodragović ZM, Andjelković KK, Radulović MD, Juranić NO, " Synthesis, NMR, DFT and antimicrobial studies of the Zn(II) complexes with N-benzyloxycarbonyl-S-alanine" J. Serb. Chem. Soc. 73(2008) 813-822.

Miodragović DU, Bogdanović GA, Miodragović ZM, Radulović MD, Novaković SB, Kaluđerović GN,  Kozłowski H, "Interesting coordination abilities of antiulcer drug famotidine and antimicrobial activity of drug and its cobalt(III) complex", J. Inorg. Biochem. 100 (2006) 1568-1574.http://www.sciencedirect.com.turing.library.northwestern.edu/science/article/pii/S0162013406001607

Miodragović ZM, Bogdanović GA, Krajčinović BB, Drakulić BJ, Kusigerski VB, Miodragović DU,  Spasojević VV, Hodžić IM, Juranić IO, "Synthesis, structure and magnetic properties of the first copper(II) complex with an (E)-4-aryl-4-oxo-2-butenoato ligand", Inorganic Chemistry Communications  9 (2006) 1173–1177.http://www.sciencedirect.com.turing.library.northwestern.edu/science/article/pii/S1387700306002917

Miodragović DU, Miodragović ZM,  Skala D, Malinar MJ and Minić DM, "Mixed cobalt(III) complexes with aromatic amino acids and diamine. Part V. Thermal investigation of (1,2-diaminoethane)bis(S-tyrosinato)cobalt(III) complex diastereomers", Thermochimica Acta 436 (2005) 90-95.http://www.sciencedirect.com.turing.library.northwestern.edu/science/article/pii/S0040603104003090

Miodragović DU, Vitnik ŽJ, Milosavljević SM, Malinar MJ, and Juranić IO, "NH…π Interactions Stabilize the Most-Hindered Rotamer of the (S)-Tyrosinato Side Group in Bis[(S)-tyrosinato](diamine)cobalt(III) Complexes: An NMR Spectroscopic and DFT Study, Eur. J. Inorg. Chem. (2005) 3172-3178. http://onlinelibrary.wiley.com/doi/10.1002/ejic.200400873/abstract

Miodragović DU, Milosavljević SM, Malinar MJ, Ćelap MB, Todorović N, Juranić N, "Mixed Cobalt(III) complexes with Aromatic amino Acids and Diamine. Part IV. Influence of Noncovalent Intra- and Interligand Interactions on Rotamer Population of the S-phenylalaninato and S-tyrosinato side groups in (1,2-Diaminoethane)bis(S-aminocarboxylato)cobalt(III) Complexes", Enantiomer  7 (2002) 375-382.

Bogdanović GA, Miodragović DU, Malinar MJ, "Mixed cobalt(III) complexes with aromatic amino acids and diamines. III.  Absolute structure of Δ-trans(O)-(1,2-diaminoethane-k2N,N)bis(S-tyrosinato)cobalt(III)chloride tetrahydrate", Acta Cryst. C 58 (2002) 338-340. 
http://dx.doi.org/10.1107/S0108270102006728

Miodragović DU, Malinar MJ, Milosavljević SM, Zarić SD, Vučelić D, Ćelap MB, "Synthesis and Absolute Configuration of Novel Mono- and Dinuclear Cobalt(III) Complexes containing S-phenylalanine", J. Coord. Chem. 55 (2002) 517-526.

Miodragović DU, Bogdanović GA, Milosavljević SM, Malinar MJ, Ćelap MB, Spasojević-de Bire A, Macura S, Juranić N, "Mixed Cobalt(III) Complexes with Aromatic Amino Acids and Diamine. Part II. Synthesis and Configuration of (1,2-diaminoethane)Bis(L-Tyrosinato)Cobalt(III) Complex Diastereomers. The  Crystal Structure of Δ-C1-Cis(O)-Diastereomer", Enantiomer  6 (2001) 299-308.

Malinar MJ, Miodragović DU, Ćelap MB, Vuković D,  Zakrzewska JS, Vučelić D, "Mixed Cobalt(III)  complexes with S-tyrosine and 1,3-Diaminopropane",  Enantiomer  3 (1998) 349-356.
 
Malinar MJ, Miodragović DU, Ćelap MB, Vuković D, Zakrzewska JS, Vučelić D,  "Mono- and dinuclear cobalt(III) complexes with S-tyrosine", J. Coord. Chem.  42 (1997) 343-351.

 

Selected Exhibitions

PRESENTATIONS

Ninth Annual Student Center for Science Engagement Research Symposium, NEIU, November 16, 2018.

Seventh Annual Student Center for Science Engagement Research Symposium, NEIU, November 18, 2016.

Fifth Annual Research & Creative symposium, Northeastern Illinois University, Chicago, November 14, 2014.

Northeastern Illinois University Fourth Annual Research & Creative Activity Symposium, Chicago, November, 25, 2013.

SMASH 2012, Providence, Rhode Island, September 9th-12th, 2012.

9th European Biological Inorganic Chemistry Conference, Wroclaw, Poland, September 2-6, 2008.

2nd European Conference on Chemistry for Life Sciences, Wroclaw, Poland, September 4-8, 2007.

2nd European Conference on Chemistry for Life Sciences, Wroclaw, Poland, September 4-8, 2007,

5th ICOSECS, Ohrid, September 10-14, 2006.

1st European Chemistry Congress, Budapest, Hungary, August 27-31, 2006.

X International Symposium on Bioinorganic Chemistry, Szklarska Poreba, Poland, September 20-25, 2005.

X International Symposium on Bioinorganic Chemistry, Szklarska Poreba, Poland, September 20-25, 2005.

4th International Conference of the Chemical Societies of the South-East European Countries on Chemical Sciences in Changing Times: Visions, Challenges and Solutions, Belgrade, Serbia and Montenegro, July 18-21, 2004.

7th International Conference on Fundamental and Applied Aspects of Physical Chemistry, Belgrade, Yugoslavia, September 21-23, 2004.

7th International Conference on Fundamental and Applied Aspects of Physical Chemistry, Belgrade, Yugoslavia, September 21-23, 2004.

Fourth Yugoslav Materials Research Society Conference ²YUCOMAT², Herceg Novi,Yugoslavia, September 10-14, 2001.

5th International Conference on Fundamental and Applied Aspects of Physical Chemistry, Belgrade, Yugoslavia, September 2000.

1st International Conference of the Chemical Societies of the South-East European Countries, Halkidiki, Greece, June 1-4, 1998.

6th International Conference on Circular Dichroism, Pisa, Italy, September 21-24,1997.

6th International Conference on Circular Dichroism, Pisa, Italy, September 21-24,1997.

 

Background

Professional Experience

Instructor, Northeastern Illinois University (2013-present)

Adjunct Faculty, Northeastern Illinois University (2011-2012)

Visiting Scholar, Northwestern University (2012-present)

Adjunct Professor of Chemistry, Wilbur Wright College (2012-2013)

Research Associate, Northwestern University (2009-2011)

Sabbatical, Northwestern University (2008-2009)     

Assistant Professor, Faculty of Chemistry, University of Belgrade (2003-2009)

Additional Information

AWARDS

Educational Leave Award 2019

Student Choice Award, NEIU, 2016.

Research Award, Ministry of Science of the Republic of Serbia, 2004

PATENTS

 Miodragovic DU and O’Halloran TV, US Patent No. 10118938, November 6, 2018

Miodragovic DU and O’Halloran TV, US Patent No. 9725475, August 8, 2017.

Miodragovic DU and O’Halloran TV, US Patent No. 9499574, November 22, 2016.

GRANTS (Co-researcher)

1UO1CA151461-01- "Tumor Targeted Nanobins for the Treatment of Metastatic Breast and Ovarian Cancer"  (2009-2011).

W.M. Keck Foundation Grant, "The Inorganic Signature of Life: Signaling Pathways in the Mammalian Oocyte"(2008 - 2009).

Synthesis, characterization and activity of organic and coordination compounds, and their appliance in (bio)nanotechnology (2005-2010).

Synthesis and structure of potentially anti-cancer platinum(IV) complexes and simmilar coordination compounds (2002-2005).

Physico-chemical, structural and biological investigation of complex compounds (2002-2005).

PROFESSIONAL SERVICES

Reviewer for the Journal of Serbian Chemical Society (from 2019)

The representative of Serbia in European Association for Chemical and Molecular Science, Division of Chemistry in Life Sciences (2006-2010)

Peer reviewer for: Inorganica Chimica Acta, Spectrochimica Acta Part A, Bioinorganic Chemistry and Application, The Arabian Journal for Science and Engineering (2003-2008)

MEMBERSHIP

American Chemical Society     2010-present

Serbian Chemical Society        2003-2008

BBH 212E
Northeastern Illinois University
5500 North St. Louis Avenue
Chicago, IL 60625
United States

Phone
(773) 442-5773
Office Hours
M, W: 10:30 -11:30 a.m.
MTWR: 4-5 p.m.
Main Campus